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In the West Indies where this term originated (especially Jamaica), a spliff is simply a marijuana cigarette, normally containing no tobacco

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A big complaint from many smokers is the lingering smell of stale tobacco that is left on your clothes, or in your car or home

Cognitive effects, such as slower motor reflexes, and severe signs like seizures, delirium, and hallucinations can also occur

Vitamin supplementation was given to most patients in the trial and pemetrexed related side effects were significantly less in patients receiving pemetrexed when they also received daily oral folate 500mcg and intramuscular vitamin B 12 1000mcg every 9 weeks compared with patients receiving pemetrexed without vitamin supplementation